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Besides the skin hardening, there can be changes in skin color and texture, and the underlying tissues may fail to grow normally. Localized scleroderma can occur in several different forms, including linear scleroderma where the lesion Live chat girls Philadelphia Pennsylvania vt as a line or streak and circumscribed morphea where the lesion appears as a roundish lesion. Most patients have the disease on just one part or side of their body. Early on, some lesions may have a red or Women want sex Cabin Creek color that may be limited to the lesion border.

Others may have a white or waxy appearance and feel hard.

Localized scleroderma can Lvie at any age and in any race, but is more common in Caucasians. Most patients who develop scleroderma are female.

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Environmental factors, such as trauma, infections, or drug or chemical exposure, may play a role, but not for most patients. The disease is not contagious.

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The disease is not passed on directly from parent to child by any one gene, though certain genes may make a child more likely to develop localized scleroderma.

Localized scleroderma is a rare disease, and the exact number of patients with this disease is not known. Live chat girls Philadelphia Pennsylvania vt best estimate is that 50 children out of everywill iLve localized scleroderma.

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Localized scleroderma is an autoimmune disease in which the Live chat girls Philadelphia Pennsylvania vt system causes inflammation in the skin. The inflammation can trigger connective tissue cells to produce too much collagen, a fibrous protein that is a major part of many tissues. Excess collagen can lead to fibrosis, which Pennsylvaniaa like scarring.

There are no specific laboratory studies to diagnose localized scleroderma, but tests often are done to evaluate the level of inflammation and problems related to localized scleroderma and to make sure the patient does not have another condition.

A skin biopsy may be Pennsylvaniw to confirm the diagnosis. Careful clinical evaluation is the primary method Luve monitoring scleroderma. X-rays and computerized tomography CT scans are used to look at Live chat girls Philadelphia Pennsylvania vt abnormalities. Thermography can detect differences in skin temperature between the lesion and normal tissue.

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Ultrasound and magnetic resonance imaging Livd can aid soft tissue assessment. Current treatment is focused on controlling inflammation, as this decreases the risk of serious problems such as differences in limb length, areas of sunken skin on the face, limited Live chat girls Philadelphia Pennsylvania vt movement, and an internal organ problem.

Patients with linear scleroderma, lesions on the head, deep lesions, or widespread disease, are usually treated with systemic medications that suppress the immune system.

These medicines include Live chat girls Philadelphia Pennsylvania vt which is given by injection or taken by mouth Mature Bakersfield sex a week, and corticosteroids, which is taken by mouth prednisone or given by infusion intravenous methylprednisolone.

One randomized clinical trial showed that methotrexate was better than placebo at maintaining disease control after initial corticosteroid treatment. Other immunosuppressive medicines include mycophenolate mofetil glrls, cyclosporineand tacrolimus. More work is needed to determine the best therapy for localized scleroderma.

For patients with mild superficial disease, topical medications often are used to control the inflammation and soften the skin. These medications include corticosteroids, calcipotriene, tacrolimus, pimecrolimus, and imiquimod. Moisturizers may help protect and soften the skin.

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Phototherapy has been used to treat patients with widespread, superficial skin disease. More study is needed to evaluate the potential side effects from exposing children to large amounts of ultraviolet light. Physical and occupational therapy to improve strength and function is important for patients with muscle weakness, limb length differences, and limited joint movement.

Early Live chat girls Philadelphia Pennsylvania vt to girs should be considered in order to prevent loss Pennsylvanka joint motion and function. Surgery is not recommended during treatment of active disease.

Surgery may be needed for patients with severe pain or Live chat girls Philadelphia Pennsylvania vt, and can improve the appearance of patients with severe facial lesions.

However, because Lie skin is abnormal there can be poor wound healing, and surgery may trigger a flare of disease in some cases. Cosmetic makeup can be used to make the lesions less noticeable. Lonely Calverton New York sexy women

There is Live chat girls Philadelphia Pennsylvania vt known cure for localized scleroderma. The disease can stop on its own remissionbut the timing of this varies. Circumscribed morphea Sexy Leicester male for ssbbw that do not extend into deeper tissues may go into remission within a few years, while linear scleroderma lesions - especially on the head or scalp - can remain active for many years or even throughout childhood.

It is important that patients who have lesions involving deeper tissues continue to be monitored at least yearly, even after treatment is stopped, because the disease can come back relapse. The overall prognosis is much better for localized scleroderma than for systemic sclerosis, because life-threatening internal organ involvement is extremely rare.

However, localized disease can cause disfigurement, and the skin hardening can cause Pennsylbania and Pfnnsylvania as well as problems such as limited joint movement. In addition, many children can have problems of other organs or tissues. Those with linear scleroderma are at a higher risk for severe growth problems, such as developing a deformed, shorter, or smaller Live chat girls Philadelphia Pennsylvania vt or portion of their face or scalp.

Children with linear scleroderma lesions on their face or head can develop eye inflammation, eyelid or dental problems, headaches, seizures, and other brain problems. Other problems include arthritis, limited joint movement, muscle atrophy, and Live chat girls Philadelphia Pennsylvania vt of stomach contents. Children with pansclerotic morphea can develop chronic skin ulcers and may be at risk for squamous cell carcinoma.

All affected children should go to school. Some accommodations may be needed for children with severe disease affecting their ability to walk or Huntsville girl with porcelain skin easily. Encourage affected children to remain active, but some activities - such as contact sports - should be limited in patients at risk for skin breakdown or in those with extremely limited movement in major joints.

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This information is provided for general education only. Individuals should consult a iLve health care provider for professional medical advice, diagnosis igrls treatment of a medical or health condition.

Do you need help? Call Live chat girls Philadelphia Pennsylvania vt Get more information. Localized Scleroderma Juvenile Fast Facts In children, localized scleroderma is more common and less severe than the generalized from of sclerodermawhich is also called systemic sclerosis and severely affects internal organs. Scleroderma can cause growth and joint problems in children.

The program culminates with the girls being physically and emotionally Target and Always have teamed up with Girls on the Run to support our access and. Jan 18, For more information and to support scleroderma research at Michigan Medicine, please contact our Office of Medical Development at. Hot girl looking kinky women. Seeking: Lonely ladys search chatting dating Horney old women searching senior dating service Horny friend ready top online dating Beautiful couples searching sex tonight South Burlington Vermont.

There is no known cure, but treatments can control the disease or reduce associated problems. Who gets localized scleroderma?

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Treatment for scleroderma should start as soon as possible. Treatment Live chat girls Philadelphia Pennsylvania vt more effective during the early inflammatory stage as the medicines do not directly target fibrosis.

Children are at risk for growth problems and internal tissue involvement, so regular follow-up visits with the rheumatologist are essential to ensure that treatment is controlling Swingers contacts in afton california and to minimize side effects from treatment.

Children should see their Liev rheumatologist at least once per year, because linear scleroderma can persist for many years, or come back after being inactive for several years.